Used as a selective inhibitor of NADPH oxidase (NOX) enzymes, particularly targeting NOX1, NOX2, and NOX4 isoforms. It is widely applied in research to investigate the role of reactive oxygen species (ROS) in cellular signaling pathways. Commonly utilized in studies related to oxidative stress, inflammation, cardiovascular diseases, and cancer progression. Due to its ability to reduce ROS production, it helps in evaluating the contribution of NOX-derived oxidants in disease models, especially in vascular dysfunction and neurodegenerative conditions. Also employed in preclinical studies to assess potential therapeutic strategies aimed at modulating oxidative damage in tissues.