Aureusidin is primarily known for its role as a natural pigment responsible for yellow coloration in certain flowers, particularly in snapdragons and other members of the Antirrhinum genus. Its application extends into plant biology research, where it serves as a model compound for studying flavonoid biosynthesis pathways and enzyme activity, especially chalcone isomerase and aurone synthase.

Due to its antioxidant properties, Aureusidin has attracted interest in the development of natural antioxidants for cosmetic and pharmaceutical formulations. It is investigated for potential anti-inflammatory and neuroprotective effects, making it a candidate for research in age-related cognitive disorders.

Additionally, because of its vivid color and natural origin, Aureusidin is explored as a safe, bio-based dye for textiles and food products, offering an alternative to synthetic colorants. Its stability under various pH conditions enhances its suitability for such applications.