Powelline is primarily used in research settings due to its biological activity. It exhibits insecticidal properties, making it of interest in the development of natural pesticide agents. Its ability to interfere with insect nervous systems has led to studies exploring its potential in crop protection. Additionally, powelline has shown mild pharmacological effects in preliminary studies, including possible anti-inflammatory and neuroactive properties, though it is not used clinically. Because of its structural complexity, it also serves as a model compound in synthetic organic chemistry for developing new reaction methodologies.