Aflatoxin G2 is primarily known for its toxicological significance rather than industrial or commercial applications. It is a mycotoxin produced by certain strains of Aspergillus fungi, commonly found in improperly stored agricultural commodities such as corn, peanuts, and tree nuts. Its presence is a major concern in food safety due to its potent hepatotoxic and carcinogenic properties, particularly contributing to liver cancer in humans and animals when ingested through contaminated food. Because of its high toxicity, Aflatoxin G2 is monitored closely in food and feed supplies. It is used in research settings as a reference standard for the detection, quantification, and study of mycotoxin contamination. Analytical laboratories use it to calibrate instruments and validate testing methods such as HPLC and ELISA to ensure accurate measurement of aflatoxin levels in food products. It also plays a role in toxicological studies assessing the health impacts of chronic mycotoxin exposure and in evaluating the efficacy of detoxification strategies in agriculture and food processing.