EHP-inhibitors are specialized chemicals used in shrimp aquaculture to control Enterocytozoon hepatopenaei (EHP), a microsporidian parasite causing hepatopancreatic microsporidiosis (HPM). This parasite infects the shrimp hepatopancreas, leading to growth retardation, reduced feed efficiency, and high mortality. By targeting essential proteins or disrupting the parasite's life cycle, EHP-inhibitors reduce infection intensity, improve shrimp survival and growth, and boost farm productivity. Their specific mode of action minimizes environmental impact, resistance development, and non-target effects compared to broad-spectrum antimicrobials, supporting sustainable integrated disease management.