(2S,4S)-Sacubitril
≥95%
Reagent
Code: #113180
CAS Number
149709-63-7
blur_circular Chemical Specifications
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Molecular Information
Weight
411.49 g/mol
Formula
C₂₄H₂₉NO₅
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Storage & Handling
Storage
2-8℃
description Product Description
Used primarily in the treatment of chronic heart failure, it functions as a neprilysin inhibitor. When combined with valsartan, it forms a dual-action drug that helps reduce the strain on the heart by enhancing the body's natural protective mechanisms. This combination is particularly effective in lowering the risk of cardiovascular death and hospitalization in patients with reduced ejection fraction. The drug works by preventing the breakdown of beneficial peptides that promote vasodilation, natriuresis, and diuresis, thereby improving heart function and overall cardiovascular health. It is typically prescribed as part of a comprehensive treatment plan that includes lifestyle modifications and other medications.
format_list_bulleted Product Specification
Test Parameter | Specification |
---|---|
Appearance | White To Pale Yellow Low-Melting Solid |
Purity (%) | 94.5-100% |
Infrared Spectrum | Conforms To Structure |
NMR | Conforms To Structure |
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(2S,4S)-Sacubitril
Used primarily in the treatment of chronic heart failure, it functions as a neprilysin inhibitor. When combined with valsartan, it forms a dual-action drug that helps reduce the strain on the heart by enhancing the body's natural protective mechanisms. This combination is particularly effective in lowering the risk of cardiovascular death and hospitalization in patients with reduced ejection fraction. The drug works by preventing the breakdown of beneficial peptides that promote vasodilation, natriuresis, and diuresis, thereby improving heart function and overall cardiovascular health. It is typically prescribed as part of a comprehensive treatment plan that includes lifestyle modifications and other medications.
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