PF-06454589

98%

Reagent Code: #109276
fingerprint
CAS Number 1527473-30-8

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 284.32 g/mol
Formula C₁₄H₁₆N₆O
inventory_2 Storage & Handling
Storage -20°C, airtight, dry

description Product Description

PF-06454589 is a potent and selective allosteric inhibitor of TYK2 (Tyrosine Kinase 2), a non-receptor tyrosine kinase involved in immune signaling pathways. It is primarily utilized in pharmaceutical research and development for its potential therapeutic applications in autoimmune and inflammatory diseases, such as psoriasis, rheumatoid arthritis, and inflammatory bowel disease. By specifically targeting the pseudokinase domain of TYK2, it modulates signaling through cytokines like IL-12, IL-23, and type I interferons without broadly affecting other JAK family members. Ongoing preclinical and clinical studies are evaluating its efficacy, safety, pharmacokinetics, and potential for clinical use in humans.

shopping_cart Available Sizes & Pricing

Size Availability Unit Price Quantity
inventory 10mg
10-20 days ฿28,431.00

Cart

No products

Subtotal: 0.00
Total 0.00 THB