tert-Butyl (4-bromo-2-(trifluoromethyl)benzyl)carbamate

98%

Reagent Code: #129868
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CAS Number 1299483-40-1

science Other reagents with same CAS 1299483-40-1

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 354.16 g/mol
Formula C₁₃H₁₅BrF₃NO₂
badge Registry Numbers
MDL Number MFCD32176810
inventory_2 Storage & Handling
Storage Room temperature, seal, dry

description Product Description

Used as an intermediate in the synthesis of pharmaceutical compounds, particularly in the development of bioactive molecules that target central nervous system disorders. Its structure allows for selective modification in drug design, especially in creating analogs with enhanced metabolic stability. Commonly employed in medicinal chemistry for constructing complex benzylamine derivatives. The tert-butyl carbamate (Boc) group serves as a protecting group for amines during multi-step syntheses, enabling controlled deprotection under mild acidic conditions. Also utilized in the preparation of kinase inhibitors and receptor modulators due to the electron-withdrawing nature of the trifluoromethyl and bromo substituents, which influence binding affinity and pharmacokinetic properties.

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Size Availability Unit Price Quantity
inventory 1g
10-20 days ฿15,540.00
inventory 250mg
10-20 days ฿5,280.00
tert-Butyl (4-bromo-2-(trifluoromethyl)benzyl)carbamate
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Used as an intermediate in the synthesis of pharmaceutical compounds, particularly in the development of bioactive molecules that target central nervous system disorders. Its structure allows for selective modification in drug design, especially in creating analogs with enhanced metabolic stability. Commonly employed in medicinal chemistry for constructing complex benzylamine derivatives. The tert-butyl carbamate (Boc) group serves as a protecting group for amines during multi-step syntheses, enabling co

Used as an intermediate in the synthesis of pharmaceutical compounds, particularly in the development of bioactive molecules that target central nervous system disorders. Its structure allows for selective modification in drug design, especially in creating analogs with enhanced metabolic stability. Commonly employed in medicinal chemistry for constructing complex benzylamine derivatives. The tert-butyl carbamate (Boc) group serves as a protecting group for amines during multi-step syntheses, enabling controlled deprotection under mild acidic conditions. Also utilized in the preparation of kinase inhibitors and receptor modulators due to the electron-withdrawing nature of the trifluoromethyl and bromo substituents, which influence binding affinity and pharmacokinetic properties.

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