Talatisamine is primarily used in the field of medicinal chemistry as a structural analog for the development of novel pharmaceutical agents. It serves as a key intermediate in the synthesis of certain alkaloid-based drugs, particularly those targeting neurological and cardiovascular systems. Due to its unique polycyclic framework, it is investigated for its potential bioactivity, including antiarrhythmic and neuroprotective properties. Researchers also utilize talatisamine in structure-activity relationship (SAR) studies to optimize potency and selectivity in drug candidates derived from natural alkaloids. Its application remains largely within research and early-stage drug discovery.