Used primarily in research settings as a potent antagonist of the transient receptor potential ankyrin 1 (TRPA1) ion channel, this compound is valuable for studying pain signaling pathways, particularly those involved in inflammatory and neuropathic pain. It helps modulate cellular responses to oxidative stress and noxious stimuli, making it a useful tool in neuroscience and pharmacology for investigating sensory neuron activity and developing potential analgesic therapies. Its structural features enable high selectivity and potency in blocking TRPA1 activation, which is implicated in conditions such as chronic cough, asthma, and migraine. Due to its stability and cell permeability, it is also employed in in vitro and in vivo experimental models to probe channel function and validate drug targets.