WAY-232261 is primarily used in neuroscience research as a potent and selective agonist for the ghrelin receptor (Growth Hormone Secretagogue Receptor, GHS-R1a). Its main application lies in studying the physiological roles of ghrelin signaling, including appetite regulation, energy homeostasis, and cognitive functions. Researchers use WAY-232261 to activate ghrelin pathways in preclinical models, helping to explore potential treatments for conditions such as cachexia, age-related muscle loss, and cognitive decline. Due to its high selectivity, it is valuable in distinguishing ghrelin-mediated effects from other hormonal pathways. It is not used clinically and remains a tool compound for in vitro and in vivo research.