Used in neuroscience and trauma research to quantify spectrin breakdown products resulting from calpain and caspase activation. Helps assess cellular damage in models of brain injury, stroke, and neurodegenerative diseases. Enables researchers to distinguish between necrotic and apoptotic pathways based on specific SBDP fragments. Widely applied in preclinical studies to evaluate neuroprotective drugs and therapeutic interventions. Provides a sensitive and specific method for detecting early neuronal injury in cerebrospinal fluid and brain tissue samples.