[Met5]-Enkephalin, amide is primarily used in research to study the opioid system and its effects on pain modulation. It acts as an agonist for opioid receptors, making it valuable for investigating pathways involved in analgesia and stress responses. This peptide is also utilized in studies exploring neurotransmitter regulation and its role in addiction, mood disorders, and neuroprotection. Additionally, it serves as a tool in pharmacological experiments to understand the mechanisms of opioid peptides and their potential therapeutic applications in managing chronic pain or neurological conditions.