Corticotropin Releasing Factor (CRF) bovine is primarily used in research settings to study stress responses and related physiological processes. It is widely applied in neuroscience and endocrinology to investigate the hypothalamic-pituitary-adrenal (HPA) axis, which regulates the body's response to stress. Researchers use it to understand how CRF influences the release of adrenocorticotropic hormone (ACTH) from the pituitary gland, which in turn stimulates cortisol production in the adrenal glands. This makes it valuable for studying stress-related disorders, anxiety, depression, and other conditions linked to HPA axis dysregulation. Additionally, it is utilized in pharmacological studies to develop and test potential therapeutic agents targeting CRF receptors.