Physalaemin is primarily used in research settings to study its effects on smooth muscle contraction and blood pressure regulation. It acts as a potent vasodilator, making it valuable in experiments exploring cardiovascular physiology. Additionally, its ability to stimulate salivary secretion has been utilized in studies focused on understanding salivary gland function and related disorders. In neuroscience, physalaemin is employed to investigate its role as a neuropeptide and its interactions with the central nervous system, particularly in pain perception and inflammation. Its applications are largely confined to laboratory research, contributing to advancements in pharmacology and physiology.