Astressin is primarily used in research settings to study the effects of stress on the body, particularly in relation to the corticotropin-releasing factor (CRF) system. It acts as a CRF receptor antagonist, helping to block the stress response mediated by CRF. This makes it a valuable tool in understanding stress-related disorders such as anxiety, depression, and post-traumatic stress disorder (PTSD). Additionally, it has been explored in preclinical studies for its potential to mitigate stress-induced behaviors and physiological changes, offering insights into therapeutic strategies for stress management. Its application extends to investigating the role of CRF in other conditions like irritable bowel syndrome (IBS) and addiction, where stress plays a significant role.