GNE 220 is primarily utilized in the field of medical research, particularly in the study and development of treatments for neurodegenerative diseases. Its application is significant in the context of targeting specific pathways involved in the progression of conditions such as Alzheimer's disease. Researchers employ GNE 220 to investigate its potential in modulating key biological processes that contribute to neuronal damage and cognitive decline. This compound is also explored for its efficacy in enhancing neuroprotection and reducing the accumulation of toxic proteins in the brain. Its role in preclinical studies helps in understanding the underlying mechanisms of neurodegeneration and in evaluating its potential as a therapeutic agent.