Tirasemtiv is primarily investigated for its potential in treating conditions related to muscle weakness and fatigue, particularly in neuromuscular disorders. It is known to enhance the sensitivity of muscle fibers to calcium, which can improve skeletal muscle function. This mechanism makes it a candidate for addressing symptoms in diseases like amyotrophic lateral sclerosis (ALS), where muscle strength and endurance are significantly compromised. By amplifying the response of muscles to nerve signals, it aims to improve motor performance and delay the progression of muscle-related disabilities. Research continues to explore its efficacy and safety in clinical settings.