Used in neuroscience research to quantify beta-amyloid peptides in biological samples such as brain tissue, cerebrospinal fluid, or cell culture supernatants. Helps in studying the progression and mechanisms of Alzheimer’s disease by measuring amyloid plaque accumulation, a hallmark of the disease. Enables evaluation of potential therapeutic compounds in preclinical models by monitoring changes in Aβ levels. Commonly used in drug development, biomarker validation, and neurotoxicity studies. Provides a sensitive and specific method for detecting both Aβ40 and Aβ42 isoforms, allowing researchers to assess the Aβ42/Aβ40 ratio, which is critical in understanding amyloid pathology.