Used in neuroscience research to quantify levels of the N-terminal fragment of human tau protein in biological samples such as cerebrospinal fluid or brain tissue extracts. This assay helps investigate tau pathology associated with neurodegenerative diseases, particularly Alzheimer's disease and other tauopathies. By detecting early proteolytic fragments of tau, the kit supports studies on disease progression, neuronal damage, and the effectiveness of therapeutic interventions targeting tau cleavage or aggregation. It is a valuable tool for biomarker validation in preclinical and clinical research settings.