Used in neuroscience research to quantify phosphorylated TAU protein levels in biological samples such as brain tissue extracts or cerebrospinal fluid. Helps in studying neurodegenerative diseases, particularly Alzheimer's disease and other tauopathies, by detecting abnormal TAU phosphorylation, which is associated with the formation of neurofibrillary tangles. Enables researchers to evaluate disease progression, assess the efficacy of therapeutic agents targeting TAU pathology, and support biomarker development for early diagnosis. Widely applied in preclinical studies and drug development pipelines focused on neurodegeneration.