Used in neuroscience and pharmacological research to quantify levels of orphanin FQ (nociceptin) in biological samples such as brain tissue, cerebrospinal fluid, or cell culture supernatants. Helps investigate the role of the nociceptin system in pain modulation, stress responses, anxiety, addiction, and feeding behavior. Enables researchers to assess changes in peptide concentration under experimental conditions, supporting drug development targeting the opioid receptor-like 1 (ORL-1) pathway. Commonly applied in preclinical studies to evaluate the effects of novel therapeutics on the central nervous system.