Used primarily in neuroscience research as a selective, competitive NMDA receptor antagonist that binds to the glutamate recognition site. It helps in studying excitatory neurotransmission, synaptic plasticity, and neuronal death pathways associated with overactivation of glutamate receptors. Frequently applied in animal models to investigate psychiatric and neurological disorders such as schizophrenia, epilepsy, and neurodegenerative diseases. Its ability to block NMDA receptor activity makes it a valuable tool for probing the role of these receptors in learning, memory, and behavior.