Used in research settings as a potent and selective antagonist for the neurokinin-1 (NK1) receptor, CP 1282 helps in studying the role of substance P in various physiological and pathological processes. It has been applied in neuroscience to investigate mechanisms related to pain transmission, inflammation, and emesis (vomiting). Due to its ability to cross the blood-brain barrier, it is valuable in central nervous system studies, particularly in developing antiemetic therapies and exploring potential treatments for anxiety, depression, and neurodegenerative conditions. Its high selectivity makes it a useful tool in receptor binding assays and pharmacological profiling.