VU 0357121
10mM in DMSO
Reagent
Code: #245227
CAS Number
433967-28-3
science Other reagents with same CAS 433967-28-3
blur_circular Chemical Specifications
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Molecular Information
Weight
305.32 g/mol
Formula
C₁₇H₁₇F₂NO₂
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Registry Numbers
MDL Number
MFCD03243692
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Storage & Handling
Storage
-20°C
description Product Description
Used as a selective positive allosteric modulator of the M4 muscarinic acetylcholine receptor, this compound is primarily employed in neuroscience research to study cholinergic signaling pathways. It helps investigate the role of M4 receptors in regulating dopamine transmission, with potential relevance to disorders such as schizophrenia, Parkinson’s disease, and substance use disorders. Due to its ability to enhance receptor specificity without activating other muscarinic subtypes, it serves as a valuable tool for probing synaptic function and developing targeted therapeutics. Preclinical studies use it to assess cognitive, antipsychotic, and motor control effects in animal models.
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