VU 0357121

10mM in DMSO

Reagent Code: #245227
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CAS Number 433967-28-3

science Other reagents with same CAS 433967-28-3

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Weight 305.32 g/mol
Formula C₁₇H₁₇F₂NO₂
badge Registry Numbers
MDL Number MFCD03243692
inventory_2 Storage & Handling
Storage -20°C

description Product Description

Used as a selective positive allosteric modulator of the M4 muscarinic acetylcholine receptor, this compound is primarily employed in neuroscience research to study cholinergic signaling pathways. It helps investigate the role of M4 receptors in regulating dopamine transmission, with potential relevance to disorders such as schizophrenia, Parkinson’s disease, and substance use disorders. Due to its ability to enhance receptor specificity without activating other muscarinic subtypes, it serves as a valuable tool for probing synaptic function and developing targeted therapeutics. Preclinical studies use it to assess cognitive, antipsychotic, and motor control effects in animal models.

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inventory 1ml
10-20 days ฿8,930.00

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VU 0357121
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Used as a selective positive allosteric modulator of the M4 muscarinic acetylcholine receptor, this compound is primarily employed in neuroscience research to study cholinergic signaling pathways. It helps investigate the role of M4 receptors in regulating dopamine transmission, with potential relevance to disorders such as schizophrenia, Parkinson’s disease, and substance use disorders. Due to its ability to enhance receptor specificity without activating other muscarinic subtypes, it serves as a valuable tool for probing synaptic function and developing targeted therapeutics. Preclinical studies use it to assess cognitive, antipsychotic, and motor control effects in animal models.
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