IKK-IN-1 is primarily used in research settings to study the IκB kinase (IKK) complex, which plays a critical role in the NF-κB signaling pathway. By inhibiting IKK activity, this compound helps researchers investigate the effects of blocking NF-κB activation, which is involved in inflammation, immune responses, and cell survival. It is particularly useful in understanding diseases like cancer, autoimmune disorders, and chronic inflammatory conditions, where NF-κB signaling is often dysregulated. Additionally, IKK-IN-1 serves as a tool for developing potential therapeutic strategies targeting the IKK/NF-κB pathway.