Chlorisondamine iodide is primarily used in medical research as a ganglionic blocking agent. It effectively inhibits the transmission of nerve impulses in autonomic ganglia, making it valuable for studying the sympathetic and parasympathetic nervous systems. This compound has been utilized in experimental models to investigate hypertension and other conditions related to autonomic dysfunction. Additionally, it has been explored for its potential to reduce blood pressure in acute hypertensive crises. Its ability to block nicotinic acetylcholine receptors also makes it a tool for understanding the role of these receptors in various physiological processes.