2,6-Bis(benzyloxy)-3-iodopyridine
95%
Reagent
Code: #131976
CAS Number
2259853-06-8
blur_circular Chemical Specifications
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Molecular Information
Weight
417.24 g/mol
Formula
C₁₉H₁₆INO₂
thermostat
Physical Properties
Boiling Point
485.2±45.0 °C(Predicted)
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Storage & Handling
Density
1.522±0.06 g/cm3(Predicted)
Storage
2-8°C, away from light, dry
description Product Description
Used as an intermediate in pharmaceutical synthesis, particularly in the development of nicotinic acetylcholine receptor modulators. It serves as a building block in the preparation of bioactive pyridine derivatives due to the presence of the iodine atom, which allows further functionalization via cross-coupling reactions such as Suzuki or Heck reactions. The benzyloxy groups act as protecting groups for phenolic functionalities and can be removed selectively under mild conditions to yield hydroxylated pyridine compounds. Commonly employed in medicinal chemistry for constructing complex heterocyclic systems found in neuroactive agents and anti-inflammatory compounds.
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