Used in the synthesis of rilpivirine, a non-nucleoside reverse transcriptase inhibitor (NNRTI) employed in the treatment of HIV-1 infection. Acts as a key intermediate in pharmaceutical manufacturing, enabling the construction of the pyrimidine core structure essential for antiviral activity. Its brominated nitrile functionality allows for selective cross-coupling reactions, facilitating efficient and scalable production of the active drug substance. Widely utilized in late-stage functionalization during API development due to its reactivity and stability under controlled conditions.