Volatile Organic Compounds (VOCs) mixed in methanol are widely used in various industrial and research applications due to their ability to provide precise and controlled concentrations of VOCs in a solvent medium. One primary application is in environmental testing and analysis, where these mixtures serve as calibration standards for gas chromatography (GC) and mass spectrometry (MS) instruments. This ensures accurate detection and quantification of VOCs in air, water, and soil samples, which is critical for monitoring pollution and ensuring compliance with environmental regulations. In the manufacturing sector, VOCs in methanol are utilized as reference materials for quality control in the production of paints, coatings, adhesives, and solvents. They help verify the composition and consistency of products, ensuring they meet industry standards. Additionally, these mixtures are employed in research laboratories for studying the behavior, degradation, and impact of VOCs on human health and the environment. They are also used in the development of air purification systems and sensors designed to detect and remove harmful VOCs from indoor and outdoor environments.