Fmoc-Leu-OH-15N
Abundance: 99atom%; Chemical Purity: ≥98%
Reagent
Code: #92754
CAS Number
200937-57-1
blur_circular Chemical Specifications
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Molecular Information
Weight
354.41 g/mol
Formula
C₂₁H₂₃₁₅NO₄
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Registry Numbers
MDL Number
MFCD00209748
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Physical Properties
Melting Point
152-156 °C(lit.)
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Storage & Handling
Storage
room temperature
description Product Description
This chemical is primarily used in peptide synthesis, particularly in solid-phase peptide synthesis (SPPS) methods. It serves as a protected amino acid derivative, where the Fmoc (fluorenylmethyloxycarbonyl) group acts as a temporary protecting group for the amino group of leucine. The incorporation of the nitrogen-15 isotope (^15N) allows for applications in nuclear magnetic resonance (NMR) spectroscopy, enabling researchers to study peptide structures and dynamics with enhanced sensitivity and resolution. It is especially valuable in isotopic labeling studies for protein and peptide research, aiding in the understanding of molecular interactions, folding, and conformational changes. Additionally, it is utilized in the development of pharmaceuticals and bioactive peptides, where precise structural analysis is critical.
format_list_bulleted Product Specification
| Test Parameter | Specification |
|---|---|
| Isotopic Purity (15N) | 99-100 atom% |
| Melting Point | 152-156 |
| Purity | 98-100% |
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