7-Chlorokynurenic acid is primarily used in neuroscience research as a selective and competitive antagonist of the glycine site on the NMDA receptor. By blocking this site, it helps in studying the role of NMDA receptors in various neurological processes, including synaptic plasticity, learning, and memory. Additionally, it is utilized in investigations related to neuroprotective strategies, as modulating NMDA receptor activity can influence outcomes in conditions like stroke, epilepsy, and neurodegenerative diseases. Its application extends to exploring potential therapeutic interventions for psychiatric disorders, such as schizophrenia, where NMDA receptor dysfunction is implicated.