Kynurenic acid
98%
Reagent
Code: #110867
Alias
4-Hydroxy-2-quinolinecarboxylic acid
4-Hydroxyquinoline-2-carboxylic acid
CAS Number
492-27-3
blur_circular Chemical Specifications
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Molecular Information
Weight
189.17 g/mol
Formula
C₁₀H₇NO₃
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Registry Numbers
EC Number
207-751-5
MDL Number
MFCD00006753
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Physical Properties
Melting Point
275 °C (dec.)(lit.)
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Storage & Handling
Storage
room temperature
description Product Description
Kynurenic acid is utilized in neuroscience research due to its role as an antagonist of excitatory amino acid receptors, particularly the NMDA receptor. This property makes it valuable in studying neurological disorders such as schizophrenia, epilepsy, and Alzheimer's disease, where glutamate signaling is often dysregulated. Additionally, it is explored for its potential neuroprotective effects, as it may help mitigate excitotoxicity, a process linked to neuronal damage in conditions like stroke and traumatic brain injury. In the field of immunology, kynurenic acid is investigated for its anti-inflammatory properties, as it influences immune responses and may modulate conditions like inflammatory bowel disease. Its presence in the gut microbiome also highlights its potential role in maintaining gut health and influencing systemic inflammation.
format_list_bulleted Product Specification
| Test Parameter | Specification |
|---|---|
| Purity (HPLC) | 98-100 |
| Purity (Neutralization Titration) | 98-100 |
| Water (By Karl Fischer) | 0-11 |
| Appearance | Light yellow or light brown crystalline powder |
| Solubility in 1 M NaOH | Yellow to brown, clear to slightly hazy, 50 mg/mL |
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