Widely utilized in neuroscience research, it serves as a potent and selective antagonist for the NMDA receptor, effectively blocking its activity. This property makes it invaluable in studies examining excitotoxicity, a process linked to neuronal damage in conditions such as stroke, traumatic brain injury, and neurodegenerative diseases like Alzheimer's. Additionally, it is employed in behavioral research to investigate the role of NMDA receptors in learning, memory, and psychiatric disorders, including schizophrenia. Its ability to induce psychotomimetic effects in animal models also aids in understanding the mechanisms underlying psychosis. Furthermore, it is used in pharmacological studies to explore potential therapeutic strategies targeting glutamate signaling pathways.