Used primarily in research settings to study the Nrf2 signaling pathway, which plays a critical role in cellular defense mechanisms against oxidative stress. By inhibiting Nrf2, researchers can better understand its function in diseases such as cancer, neurodegenerative disorders, and chronic inflammation. It helps in evaluating the potential of targeting Nrf2 for therapeutic interventions, particularly in conditions where Nrf2 overexpression contributes to disease progression or resistance to treatment. Additionally, it aids in exploring the balance between oxidative stress protection and its role in promoting tumor survival.