Used in molecular biology to stabilize and protect RNA during isolation and purification processes, particularly from tissues rich in polyphenols or polysaccharides. The RNase-free formulation helps prevent RNA degradation by binding to contaminants that can inhibit purification or promote enzymatic breakdown, without introducing RNase contamination. Commonly added to lysis buffers or extraction protocols to ensure high-quality RNA for downstream applications like PCR, sequencing, or gene expression analysis. Its effectiveness makes it a valuable component in RNA-related research and diagnostics.