3',5'-O-(1,1,3,3-Tetraisopropyl-1,3-disiloxanediyl)-5-methyluridine
95%
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description Product Description
This compound is primarily used in the field of nucleic acid chemistry and oligonucleotide synthesis. It serves as a protected nucleoside, where the 3' and 5' hydroxyl groups are shielded by a tetraisopropyldisiloxane (TIPDS) group, allowing selective modification or elongation of the nucleic acid chain. This protection is crucial in the synthesis of RNA molecules, particularly in the preparation of modified nucleosides for research or therapeutic purposes. Its application is significant in the development of antisense oligonucleotides, siRNA, and other RNA-based therapeutics, where precise control over the structure and function of the molecule is required. Additionally, it is utilized in the study of RNA metabolism and in the creation of labeled nucleosides for biochemical assays.
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