7-Deaza-7-iodo-2',3'-dideoxyadenosine

97%

Reagent Code: #97065
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CAS Number 114748-70-8

blur_circular Chemical Specifications

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Weight 360.15 g/mol
Formula C₁₁H₁₃IN₄O₂
inventory_2 Storage & Handling
Storage 2-8℃

description Product Description

7-Deaza-7-iodo-2',3'-dideoxyadenosine is a modified nucleoside analog primarily used as a synthetic intermediate in biochemical research. The iodine substituent at the 7-position enables further chemical modifications, such as cross-coupling reactions, to generate diverse 7-substituted-7-deaza-dideoxyadenosine derivatives. These derivatives serve as tools for studying nucleic acid interactions, enzyme mechanisms, and DNA/RNA synthesis processes, often acting as chain terminators to halt nucleic acid chain elongation. This makes them valuable for DNA sequencing and investigating polymerase functions. Additionally, such analogs are employed in developing antiviral and anticancer agents by interfering with viral or tumor DNA replication, particularly targeting reverse transcriptase in RNA viruses. Researchers also use them to explore the impacts of nucleoside modifications on cellular metabolism and gene expression.

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Size Availability Unit Price Quantity
inventory 100mg
10-20 days ฿113,148.00

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