Used in the synthesis of oligonucleotides, particularly in the development of modified nucleic acids for research and therapeutic applications. It serves as a key building block in the creation of fluorinated DNA or RNA sequences, enhancing stability and resistance to enzymatic degradation. This chemical is valuable in antisense technology, gene silencing, and the study of nucleic acid interactions. Its incorporation into oligonucleotides can improve binding affinity and specificity, making it useful in diagnostic assays and drug development targeting genetic disorders or viral infections.