1-((2R,4S,5R)-4-((tert-butyldimethylsilyl)oxy)-5-(((tert-butyldimethylsilyl)oxy)methyl)tetrahydrofuran-2-yl)-5-methylpyrimidine-2,4(1H,3H)-dione
95%
Reagent
Code: #82422
CAS Number
40733-26-4
science Other reagents with same CAS 40733-26-4
blur_circular Chemical Specifications
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Molecular Information
Weight
470.75 g/mol
Formula
C₂₂H₄₂N₂O₅Si₂
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Registry Numbers
MDL Number
MFCD01631042
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Storage & Handling
Storage
2-8°C
description Product Description
This compound is primarily used in the synthesis of nucleoside analogs, which are crucial in the development of antiviral and anticancer drugs. Its structure, featuring protected hydroxyl groups, allows for precise manipulation in organic synthesis, particularly in the construction of complex nucleotide frameworks. The tert-butyldimethylsilyl (TBDMS) groups serve as protective moieties, ensuring selective reactivity during multi-step synthetic processes. This chemical is often employed in the preparation of modified nucleosides that target viral polymerases or cellular enzymes, making it valuable in medicinal chemistry research. Additionally, it plays a role in the study of nucleic acid interactions and the development of therapeutic agents for diseases like HIV, hepatitis, and certain cancers.
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