1-((2R,4S,5R)-4-((tert-butyldimethylsilyl)oxy)-5-(((tert-butyldimethylsilyl)oxy)methyl)tetrahydrofuran-2-yl)-5-methylpyrimidine-2,4(1H,3H)-dione

95%

Reagent Code: #82422
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CAS Number 40733-26-4

science Other reagents with same CAS 40733-26-4

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 470.75 g/mol
Formula C₂₂H₄₂N₂O₅Si₂
badge Registry Numbers
MDL Number MFCD01631042
inventory_2 Storage & Handling
Storage 2-8°C

description Product Description

This compound is primarily used in the synthesis of nucleoside analogs, which are crucial in the development of antiviral and anticancer drugs. Its structure, featuring protected hydroxyl groups, allows for precise manipulation in organic synthesis, particularly in the construction of complex nucleotide frameworks. The tert-butyldimethylsilyl (TBDMS) groups serve as protective moieties, ensuring selective reactivity during multi-step synthetic processes. This chemical is often employed in the preparation of modified nucleosides that target viral polymerases or cellular enzymes, making it valuable in medicinal chemistry research. Additionally, it plays a role in the study of nucleic acid interactions and the development of therapeutic agents for diseases like HIV, hepatitis, and certain cancers.

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Size Availability Unit Price Quantity
inventory 100mg
10-20 days ฿14,040.00
inventory 250mg
10-20 days ฿23,400.00
inventory 1g
10-20 days ฿46,800.00

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1-((2R,4S,5R)-4-((tert-butyldimethylsilyl)oxy)-5-(((tert-butyldimethylsilyl)oxy)methyl)tetrahydrofuran-2-yl)-5-methylpyrimidine-2,4(1H,3H)-dione
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This compound is primarily used in the synthesis of nucleoside analogs, which are crucial in the development of antiviral and anticancer drugs. Its structure, featuring protected hydroxyl groups, allows for precise manipulation in organic synthesis, particularly in the construction of complex nucleotide frameworks. The tert-butyldimethylsilyl (TBDMS) groups serve as protective moieties, ensuring selective reactivity during multi-step synthetic processes. This chemical is often employed in the preparation of modified nucleosides that target viral polymerases or cellular enzymes, making it valuable in medicinal chemistry research. Additionally, it plays a role in the study of nucleic acid interactions and the development of therapeutic agents for diseases like HIV, hepatitis, and certain cancers.
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