Used primarily in the synthesis of oligonucleotides, it serves as a key building block in the production of DNA and RNA sequences. The dimethoxytrityl (DMT) group acts as a protecting group for the 5'-hydroxyl function during solid-phase synthesis, ensuring selective reactions at other sites. This compound is crucial in the development of nucleic acid-based therapeutics, including antisense oligonucleotides and siRNA, which are employed in gene silencing and targeted therapy for various diseases. Additionally, it is utilized in research laboratories for the study of nucleic acid structure and function, as well as in the creation of probes for diagnostic applications.