TH287

>98%

Reagent Code: #102900
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CAS Number 1609960-30-6

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 269.13 g/mol
Formula C₁₁H₁₀Cl₂N₄
inventory_2 Storage & Handling
Storage 2-8℃

description Product Description

TH287 is primarily utilized in the field of cancer research due to its role as a potent inhibitor of MTH1, an enzyme that helps cancer cells survive by preventing the incorporation of damaged nucleotides into DNA. By inhibiting MTH1, TH287 induces DNA damage and selectively targets cancer cells, making it a promising candidate for developing novel anticancer therapies. It is often used in preclinical studies to explore its efficacy in various cancer models, particularly in understanding the mechanisms of DNA repair and cell death pathways. Additionally, TH287 serves as a valuable tool in biochemical assays to study the function of MTH1 and its impact on cellular processes. Its potential to enhance the effectiveness of existing cancer treatments, such as chemotherapy, is also under investigation.

format_list_bulleted Product Specification

Test Parameter Specification
Appearance White to Beige Solid
Purity (%) 98-100%
Solubility DMSO: 5 Mg/Ml, Clear (Warmed)

shopping_cart Available Sizes & Pricing

Size Availability Unit Price Quantity
inventory 10mg
10-20 days ฿7,350.00
inventory 5mg
10-20 days ฿5,250.00
TH287
TH287 is primarily utilized in the field of cancer research due to its role as a potent inhibitor of MTH1, an enzyme that helps cancer cells survive by preventing the incorporation of damaged nucleotides into DNA. By inhibiting MTH1, TH287 induces DNA damage and selectively targets cancer cells, making it a promising candidate for developing novel anticancer therapies. It is often used in preclinical studies to explore its efficacy in various cancer models, particularly in understanding the mechanisms of DNA repair and cell death pathways. Additionally, TH287 serves as a valuable tool in biochemical assays to study the function of MTH1 and its impact on cellular processes. Its potential to enhance the effectiveness of existing cancer treatments, such as chemotherapy, is also under investigation.
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