TH588
>98%
Reagent
Code: #102904
CAS Number
1609960-31-7
blur_circular Chemical Specifications
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Molecular Information
Weight
295.17 g/mol
Formula
C₁₃H₁₂Cl₂N₄
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Storage & Handling
Storage
-20℃
description Product Description
TH588 is primarily investigated for its potential applications in cancer research due to its ability to selectively target and inhibit MTH1, an enzyme that plays a role in DNA repair mechanisms. By disrupting MTH1, it induces oxidative DNA damage in cancer cells, leading to their death while sparing healthy cells. This makes it a promising candidate for developing targeted cancer therapies. Additionally, it is studied for its effects on neurodegenerative diseases, as oxidative stress is a key factor in conditions like Alzheimer's and Parkinson’s. Researchers are exploring its utility in understanding cellular mechanisms and developing treatments for these diseases.
format_list_bulleted Product Specification
Test Parameter | Specification |
---|---|
Appearance | White to off-white solid |
Purity (%) | 100% |
Infrared Spectrum | Conforms To Structure |
NMR | Conforms To Structure |
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TH588
TH588 is primarily investigated for its potential applications in cancer research due to its ability to selectively target and inhibit MTH1, an enzyme that plays a role in DNA repair mechanisms. By disrupting MTH1, it induces oxidative DNA damage in cancer cells, leading to their death while sparing healthy cells. This makes it a promising candidate for developing targeted cancer therapies. Additionally, it is studied for its effects on neurodegenerative diseases, as oxidative stress is a key factor in conditions like Alzheimer's and Parkinson’s. Researchers are exploring its utility in understanding cellular mechanisms and developing treatments for these diseases.
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