Folinic acid is widely used in medical treatments, particularly as an antidote to counteract the toxic effects of methotrexate, a chemotherapy drug. It helps protect healthy cells from damage while allowing the chemotherapy to target cancer cells effectively. Additionally, folinic acid is employed in the treatment of folate deficiency, which can lead to anemia and other health issues. It is also used in combination with fluorouracil (5-FU) to enhance its efficacy in treating certain types of cancer, such as colorectal cancer. Beyond oncology, folinic acid supports neurological health and is sometimes used in managing conditions like cerebral folate deficiency. In prenatal care, it aids in reducing the risk of neural tube defects in developing fetuses when taken as a supplement. It also plays a role in treating toxicities from substances like methanol poisoning by supporting metabolic pathways. Furthermore, folinic acid is utilized in the production of pharmaceuticals and nutritional supplements to enhance therapeutic and nutritional value. Its role in DNA synthesis and repair makes it valuable in various therapeutic applications.