Adenosine 5'-(γ-thio)-triphosphate (lithium salt) (ATPγS)
98%
Reagent
Code: #107526
CAS Number
93839-89-5
blur_circular Chemical Specifications
scatter_plot
Molecular Information
Weight
546.98 g/mol
Formula
C₁₀H₁₂N₅O₁₂P₃S₄Li
inventory_2
Storage & Handling
Storage
-20°C, airtight, dry
description Product Description
ATPγS is widely used in biochemical research as a non-hydrolyzable analog of ATP, making it valuable for studying ATP-dependent processes. It is particularly useful in kinase assays, where it serves as a substrate to investigate enzyme activity without being broken down. This property allows researchers to trap and analyze intermediate states of enzymatic reactions. Additionally, ATPγS is employed in studying G-protein-coupled receptor signaling pathways, as it can activate G-proteins without subsequent deactivation. It is also used in protein phosphorylation studies to create thiophosphorylated proteins, which are resistant to phosphatases, enabling the examination of phosphorylation effects over extended periods. In structural biology, ATPγS aids in stabilizing protein complexes for X-ray crystallography or cryo-EM analysis. Its applications extend to investigating nucleotide-binding proteins, ion channels, and cellular energy metabolism.
format_list_bulleted Product Specification
Test Parameter | Specification |
---|---|
Appearance | White Powder |
Purity (%) | 97.5-100% |
Infrared Spectrum | Conforms to Structure |
NMR | Conforms To Structure |
shopping_cart Available Sizes & Pricing
Adenosine 5'-(γ-thio)-triphosphate (lithium salt) (ATPγS)
ATPγS is widely used in biochemical research as a non-hydrolyzable analog of ATP, making it valuable for studying ATP-dependent processes. It is particularly useful in kinase assays, where it serves as a substrate to investigate enzyme activity without being broken down. This property allows researchers to trap and analyze intermediate states of enzymatic reactions. Additionally, ATPγS is employed in studying G-protein-coupled receptor signaling pathways, as it can activate G-proteins without subsequent deactivation. It is also used in protein phosphorylation studies to create thiophosphorylated proteins, which are resistant to phosphatases, enabling the examination of phosphorylation effects over extended periods. In structural biology, ATPγS aids in stabilizing protein complexes for X-ray crystallography or cryo-EM analysis. Its applications extend to investigating nucleotide-binding proteins, ion channels, and cellular energy metabolism.
Mechanism | - |
Appearance | - |
Longevity | - |
Strength | - |
Storage | - |
Shelf Life | - |
Allergen(s) | - |
Dosage (Range) | - |
Recommended Dosage | - |
Dosage (Per Day) | - |
Recommended Dosage (Per Day) | - |
Mix Method | - |
Heat Resistance | - |
Stable in pH range | - |
Solubility | - |
Product Types | - |
INCI | - |
Purchase History for
Loading purchase history...
Cart
No products
Subtotal:
฿0.00
Total
฿0.00
THB