Pomalidomide-5-OH is primarily utilized in the field of oncology, particularly for the treatment of multiple myeloma. It is an active metabolite of pomalidomide, which enhances its therapeutic effects. This compound works by modulating the immune system and inhibiting the growth of cancer cells. It is often employed in combination with other medications, such as dexamethasone, to improve efficacy in patients who have not responded well to previous treatments. Additionally, it plays a role in reducing angiogenesis, the process by which tumors develop new blood vessels, thereby limiting their ability to grow and spread. Its application is crucial for patients with relapsed or refractory multiple myeloma, offering a potential improvement in survival rates and quality of life.