Used in the treatment of advanced basal cell carcinoma, particularly for patients with metastatic disease or locally advanced cases that are not suitable for surgery or radiation. It functions by inhibiting the Hedgehog signaling pathway, which plays a key role in cell growth and development. When this pathway is abnormally activated, it can lead to uncontrolled cell proliferation and tumor formation. Vismodegib effectively targets and suppresses this pathway, helping to reduce tumor size and slow disease progression. It is taken orally and offers a systemic treatment option for cancers that have limited therapeutic alternatives.