JDTic is primarily used in research settings to study the kappa opioid receptor (KOR) due to its role as a highly selective antagonist. It helps in understanding the receptor's function in pain modulation, stress responses, and mood disorders. Researchers utilize JDTic to explore potential therapeutic applications for conditions like depression, anxiety, and addiction, as blocking KOR activity has shown promise in reducing stress-related behaviors and drug-seeking tendencies. Additionally, its long-lasting effects make it a valuable tool for preclinical studies aimed at developing novel treatments for neurological and psychiatric disorders.