JTC-801 is primarily utilized in research settings for its role as a selective antagonist of the nociceptin receptor (NOP). This receptor is involved in the modulation of pain and anxiety, making JTC-801 a valuable tool in studying pain pathways and the development of potential analgesic drugs. Researchers use it to investigate the mechanisms underlying chronic pain conditions and to explore new therapeutic strategies for pain management. Additionally, its interaction with the NOP receptor provides insights into the regulation of stress and anxiety-related behaviors, contributing to the broader understanding of neurological and psychiatric disorders.