6α-Naltrexol is primarily used in research and clinical studies focused on opioid receptor modulation. It serves as a metabolite of naltrexone and has been investigated for its potential role in reducing opioid cravings and withdrawal symptoms. Its application extends to studying its effects on immune system modulation, particularly in conditions like cancer and autoimmune diseases, where it may influence cell proliferation and inflammation. Additionally, it is explored for its potential in managing chronic pain and addiction treatment protocols, offering a pathway to develop novel therapeutic strategies.